MedicInvent has conducted In Vivo animal
studies in conjunction with Oklahoma State University
to measure the efficacy of the Technology on promoting
tissue growth at the juncture of the catheter and the
cutaneous incision point and on increasing the tensile
strength and stiction at the adherence point of the tissue
growth and the catheter.
The results of MedicInvent's studies indicate
that MedicInvent's texturing design can increase and accelerate
tissue growth at the juncture of the catheter and the
cutaneous incision point and increase stiction as measured
by the tensile strength of the adherence point of the
tissue growth and the catheter. Further, MedicInvent has
demonstrated that it can implement its Technology using
a non-disruptive manufacturing process which does not
alter the diameter (gauge) or shape of the catheter.
The perceived benefits of increased and
accelerated tissue growth and increases in tensile strength
and stiction are:
The following photographs demonstrate increases
in tissue growth as a result of texturing after catheters
and Vero cells were cultured under routine cell conditions
for 48 hours (100x magnification):
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Smooth Catheter
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Textured Catheter
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The Company’s animal studies were conducted
to determine if the Company’s texturing design can
increase and accelerate tissue growth at the juncture
of the catheter and the cutaneous incision point and increase
stiction as measured by the tensile strength of the adherence
point of the tissue growth and the catheter.
The following chart demonstrates tensile
strength over time during pull test from In Vivo studies:
The Company believes that observed
increases in tensile strength were as a result of:
